Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | NPY4R | P50391 | 9/20 | 0.43 |
| ▸ | NPY1R | P25929 | 6/20 | 0.43 |
| ▸ | NPY2R | P49146 | 4/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.43 |
| ▸ | GRB2 | P62993 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368582 | 0.92 | GNPAT (0.48) | HRH4NPY4RNPY1RGRB2SMN1; SMN2 | |
| SCHEMBL7370024 | 0.88 | PSMB5 (0.46) | HRH4NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL24736900 | 0.87 | CTSC (0.45) | NPY4RNPY1RNPY2RNPY5RSMN1; SMN2 | |
| SCHEMBL3134717 | 0.87 | CTSC (0.45) | NPY4RNPY1RNPY2RNPY5RSMN1; SMN2 | |
| SCHEMBL7374882 | 0.86 | CTSS (0.56) | — | |
| SCHEMBL8373858 | 0.86 | HDAC3 (0.42) | HRH4SMN1; SMN2CASP1MMP9MMP8 | |
| SCHEMBL21167845 | 0.84 | NPY4R (0.52) | NPY4RNPY1RNPY2RNPY5RSMN1; SMN2 | |
| Sulfuric Acid SCHEMBL7302945 | 0.83 | CTSC (0.42) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL21360283 | 0.81 | GNPAT (0.52) | NPY4RNPY1RNPY2RNPY5RSMN1; SMN2 | |
| SCHEMBL29511096 | 0.81 | HRH4 (0.52) | OPRD1HRH4NPY4RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994013693-A1 | NOVEL INHIBITORS OF FACTOR Xa | CORVAS INTERNATIONAL, INC. (US) | 1994-06-23 | — | — | WO | disclosed |