Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | GLA | P06280 | 4/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378046 | 0.76 | CYP1A1 (0.56) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL7371005 | 0.75 | CYP1A2 (0.52) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL7380070 | 0.75 | HPGD (0.65) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL7374824 | 0.75 | TERT (0.65) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL7375040 | 0.75 | TERT (0.65) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL7375563 | 0.73 | TERT (0.52) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL7378981 | 0.73 | TERT (0.52) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL7374866 | 0.72 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL7371816 | 0.72 | CSNK2A2 (0.59) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL7378867 | 0.72 | CYP3A4 (0.67) | KDM4EALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115718-A1 | HYDROXYFLAVONE DERIVATIVES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017184-A1 | HYDROXYFLAVONE DERIVATIVES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-03-30 | — | — | WO | disclosed |