Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | USP1 | O94782 | 1/20 | 0.40 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369715 | 0.83 | CYP11B1 (0.52) | NPY5RCYP11B1CYP11B2TEKKMT2A | |
| SCHEMBL7370892 | 0.83 | NPY5R (0.57) | NPY5RCYP11B1CYP11B2TEKKMT2A | |
| SCHEMBL7369697 | 0.81 | NPY5R (0.54) | NPY5RCYP11B1CYP11B2TEKKMT2A | |
| SCHEMBL7370832 | 0.81 | CYP11B1 (0.52) | NPY5RCYP11B1CYP11B2KMT2AKDM4E | |
| SCHEMBL7376655 | 0.81 | MGAM (0.52) | NPY5RCYP11B1CYP11B2KMT2AKDM4E | |
| SCHEMBL27692933 | 0.79 | CYP11B1 (0.50) | NPY5RCYP11B1CYP11B2TEKTRPA1 | |
| SCHEMBL7372656 | 0.79 | ALOX5 (0.50) | NPY5RCYP11B1CYP11B2KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL7369410 | 0.78 | PDE5A (0.58) | NPY5RCYP11B1CYP11B2KMT2AALDH1A1 | |
| SCHEMBL12692422 | 0.76 | NPY5R (0.64) | NPY5RCYP11B1CYP11B2TRPA1TRPM8 | |
| SCHEMBL7372737 | 0.76 | MGAM (0.52) | NPY5RCYP11B1CYP11B2PTGESUSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |