Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28801723 | 0.76 | RAB9A (0.51) | KDM4EALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL5617566 | 0.76 | RAB9A (0.45) | KDM4EALDH1A1RAB9AHPGDNPC1 | |
| Hydrochloric Acid SCHEMBL8376217 | 0.75 | RAB9A (0.44) | KDM4EALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL12051092 | 0.70 | THRB (0.51) | KDM4EALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL508571 | 0.69 | KMT2A (0.61) | KDM4EALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL7377958 | 0.68 | ADRB2 (0.37) | ALDH1A1RAB9AHPGDNPC1SMN1; SMN2 | |
| SCHEMBL9564367 | 0.68 | RAB9A (0.52) | KDM4EALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL4140152 | 0.68 | RAB9A (0.51) | KDM4EALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL8377368 | 0.67 | RAB9A (0.40) | KDM4EALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL8375503 | 0.67 | RAB9A (0.55) | KDM4EALDH1A1RAB9AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994107-A1 | 5-Arylisoxazol-4-yl-substituted 2-amino carboxylic acid compounds | H. LUNDBECK A/S (DK) | 2000-04-19 | — | — | EP | disclosed |
| EP-0726896-A1 | 5-ARYLISOXAZOL-4-YL-SUBSTITUTED 2-AMINO CARBOXYLIC ACID COMPOUNDS | H. LUNDBECK A/S (DK) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012587-A1 | 5-ARYLISOXAZOL-4-YL-SUBSTITUTED 2-AMINO CARBOXYLIC ACID COMPOUNDS | H. LUNDBECK A/S (DK) | 1995-05-11 | — | — | WO | disclosed |