Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TEK | Q02763 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369293 | 0.87 | CYP3A4 (0.52) | MKNK1MKNK2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL7377111 | 0.85 | NPY5R (0.54) | MKNK1MKNK2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL7375472 | 0.79 | TUBB4A (0.47) | MKNK1MKNK2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL7370913 | 0.71 | NPY5R (0.57) | CYP11B1CYP11B2CYP17A1CYP3A4CYP1A1 | |
| SCHEMBL10564760 | 0.71 | TUBB4A (0.45) | CYP11B1CYP11B2TEKPDE10ATUBB4A | |
| SCHEMBL7271721 | 0.71 | PDE5A (0.53) | TEKAAK1 | |
| SCHEMBL10518202 | 0.71 | PDE5A (0.65) | TEK | |
| SCHEMBL7372225 | 0.70 | NPY5R (0.62) | MKNK1MKNK2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL7369602 | 0.70 | NPY5R (0.56) | MKNK1MKNK2CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL2817926 | 0.70 | CYP11B1 (0.49) | CYP11B1CYP19A1NPY5RCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |