Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.50 |
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372964 | 0.87 | MKNK1 (0.41) | CYP3A4CYP1A2CYP1A1CYP1B1CYP11B2 | |
| SCHEMBL7370913 | 0.84 | NPY5R (0.57) | CYP3A4CYP1A2CYP1A1CYP1B1CYP11B2 | |
| SCHEMBL7371561 | 0.78 | PDE2A (0.56) | CYP3A4CYP1A2CYP1A1CYP1B1CYP11B2 | |
| SCHEMBL7371766 | 0.77 | PDE2A (0.53) | CYP3A4CYP1A2CYP1A1CYP1B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7370882 | 0.77 | PDE2A (0.55) | CYP3A4CYP1A2CYP1A1CYP1B1CYP11B2 | |
| SCHEMBL7365842 | 0.77 | TGFBR1 (0.70) | PDE2ANPY5RNPC1 | |
| SCHEMBL7365692 | 0.76 | NPY5R (0.57) | CYP3A4CYP1A2CYP1A1CYP1B1CYP11B2 | |
| SCHEMBL7369602 | 0.73 | NPY5R (0.56) | CYP3A4CYP1A2CYP1A1CYP1B1CYP11B2 | |
| SCHEMBL7372225 | 0.73 | NPY5R (0.62) | CYP3A4CYP1A2CYP1A1CYP1B1CYP11B2 | |
| SCHEMBL2817926 | 0.72 | CYP11B1 (0.49) | CYP11B1NPY5RKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| CN-87105680-A | Imidazolium compounds and preparation method thereof and comprise the pharmaceutical composition of this compound | — | 1988-04-27 | — | — | CN | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |