Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5093810 | 1.00 | RAB9A (0.41) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7405615 | 0.94 | RAB9A (0.42) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7405620 | 0.94 | RAB9A (0.42) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9327794 | 0.90 | RAB9A (0.39) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7298375 | 0.85 | CYP3A4 (0.38) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7298371 | 0.85 | CYP3A4 (0.38) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7276975 | 0.84 | CTSK (0.37) | CTSKGAAMAPTXBP1NPSR1 | |
| SCHEMBL9326544 | 0.83 | CTSK (0.42) | CTSKGAAMAPTXBP1NPSR1 | |
| SCHEMBL5088804 | 0.81 | ELANE (0.41) | RAB9ACYP3A4CYP2C19ELANEGAA | |
| SCHEMBL9329333 | 0.81 | CTSB (0.43) | CTSKGAAMAPTXBP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777646-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 2001-09-05 | — | — | EP | disclosed |
| US-5763621-A | Metalloproteinase inhibitors | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |
| WO-1996006074-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-02-29 | — | — | WO | disclosed |