Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267261 | 0.77 | CYP11B1 (0.38) | CYP11B1CYP11B2KCNN4 | |
| SCHEMBL8188378 | 0.64 | KMT2A (0.46) | CYP11B1CYP11B2KCNN4 | |
| SCHEMBL9571783 | 0.63 | LMNA (0.32) | CYP11B1CYP11B2 | |
| SCHEMBL4025845 | 0.62 | KDM4E (0.32) | CYP11B1CYP11B2KCNN4 | |
| SCHEMBL23532128 | 0.61 | CYP11B1 (0.36) | CYP11B1CYP11B2KCNN4 | |
| SCHEMBL7269738 | 0.61 | SIRT2 (0.50) | CYP11B1CYP11B2 | |
| SCHEMBL10439558 | 0.61 | CYP1A2 (0.44) | CYP11B1CYP11B2KCNN4 | |
| SCHEMBL4806085 | 0.61 | CYP11B1 (0.43) | CYP11B1CYP11B2KCNN4 | |
| SCHEMBL7268178 | 0.60 | CYP11B1 (0.34) | CYP11B1CYP11B2 | |
| SCHEMBL7310245 | 0.59 | CYP11B1 (0.34) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866598-A | 4H-CARBAZOL-4-ONES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5698561-A | PYRIDO(1,2-A)INDOLE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| US-5607938-A | Medicament for treating or preventing cerebrovascular infarction | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0688216-A1 | MEDICAMENT FOR TREATING OR PREVENTING CEREBROVASCULAR DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-12-27 | — | — | EP | disclosed |
| EP-0420086-B1 | Pyrimidoindole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-12-13 | — | — | EP | disclosed |
| WO-1994020102-A2 | MEDICAMENT FOR TREATING OR PREVENTING CEREBROVASCULAR DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-15 | — | — | WO | disclosed |
| US-5256780-A | Serotonin antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| US-5180728-A | Antagonists of 5-hydroxytryptamine | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0420086-A2 | Pyrimidoindole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-03 | — | — | EP | disclosed |