Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPIN1 | Q9Y657 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | EBP | Q15125 | 2/20 | 0.50 |
| ▸ | SPIN4 | Q56A73 | 1/20 | 0.50 |
| ▸ | SPIN3 | Q5JUX0 | 1/20 | 0.50 |
| ▸ | SPIN2B | Q9BPZ2 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | EBPL | Q9BY08 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28610812 | 0.88 | LTA4H (0.58) | SPIN1SIGMAR1EBPTMEM97ABCB1 | |
| SCHEMBL29995464 | 0.88 | LTA4H (0.58) | SPIN1SIGMAR1EBPTMEM97ABCB1 | |
| SCHEMBL13058286 | 0.87 | TSHR (0.57) | SPIN1SIGMAR1HRH3 | |
| SCHEMBL7369533 | 0.87 | SPIN1 (0.49) | SPIN1SIGMAR1EBPSPIN4SPIN3 | |
| SCHEMBL7369485 | 0.87 | MAPK1 (0.58) | SIGMAR1EBPTMEM97EBPL | |
| SCHEMBL30764769 | 0.84 | EHMT2 (0.50) | SPIN1ABCB1HRH3 | |
| SCHEMBL5103081 | 0.84 | EHMT2 (0.50) | SPIN1ABCB1HRH3 | |
| SCHEMBL7372119 | 0.81 | HPGD (0.58) | SIGMAR1 | |
| SCHEMBL7371157 | 0.80 | DRD4 (0.58) | SIGMAR1 | |
| SCHEMBL7370004 | 0.79 | DRD2 (0.50) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929074-A | VSODILATOR, ANTIALLERGIC AND ANTIPLATELET AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| EP-0706517-B1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL IND LTD (JP) | 1998-10-21 | — | — | EP | disclosed |
| US-5728702-A | BRONCHODILATOR AGENTS, ANTIALLERGENS OR ANTIPLATELET DRUGGS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |
| CN-1126470-A | Pyridazinone derivatives | NISSAN CHEMICAL IND LTD (JP) | 1996-07-10 | — | — | CN | disclosed |
| EP-0706517-A1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001343-A1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |