Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SPIN1 | Q9Y657 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | EBP | Q15125 | 2/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28610812 | 1.00 | LTA4H (0.58) | LTA4HDRD2DRD4DRD3ABCB1 | |
| SCHEMBL7374884 | 0.88 | SPIN1 (0.54) | ABCB1SPIN1SIGMAR1EBPTMEM97 | |
| SCHEMBL28624567 | 0.84 | DRD2 (0.56) | LTA4HDRD2DRD4DRD3ABCB1 | |
| SCHEMBL29675362 | 0.84 | DRD2 (0.56) | LTA4HDRD2DRD4DRD3ABCB1 | |
| SCHEMBL6313608 | 0.83 | KDM4E (0.53) | LTA4HDRD3ABCB1KDM4EHTR1B | |
| SCHEMBL7371157 | 0.81 | DRD4 (0.58) | LTA4HDRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL7370004 | 0.80 | DRD2 (0.50) | LTA4HDRD2DRD4DRD3KDM4E | |
| SCHEMBL13103637 | 0.80 | KMT2A (0.52) | LTA4HDRD2DRD4DRD3KDM4E | |
| SCHEMBL28614770 | 0.80 | DRD2 (0.54) | LTA4HDRD2DRD4DRD3 | |
| SCHEMBL29675216 | 0.80 | DRD2 (0.54) | LTA4HDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292484-B | 3- (4-methylpiperidine-1-yl) -3-benzylurea compound and analogue, preparation method and application thereof | 沈阳药科大学 | 2022-11-15 | — | — | CN | disclosed |