Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 6/20 | 0.37 |
| ▸ | F2 | P00734 | 7/20 | 0.36 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7384671 | 0.89 | NOS1 (0.37) | NOS1F10F2RAPGEF3PRSS1 | |
| SCHEMBL7382892 | 0.88 | NCF1 (0.43) | F10F2RAPGEF3PRSS1HPGDS | |
| Trifluoroacetic Acid SCHEMBL7383810 | 0.83 | NOS1 (0.42) | NOS1NOS3F10F2PRSS1 | |
| SCHEMBL7384883 | 0.82 | F10 (0.40) | F10F2RAPGEF3 | |
| Trifluoroacetic Acid SCHEMBL7471306 | 0.79 | F2 (0.41) | F10F2RAPGEF3PRSS1HPGDS | |
| Trifluoroacetic Acid SCHEMBL7375646 | 0.79 | RAPGEF3 (0.35) | F10F2RAPGEF3PRSS1HPGDS | |
| Trifluoroacetic Acid SCHEMBL7384787 | 0.79 | NOS1 (0.36) | NOS1NOS3F10 | |
| Trifluoroacetic Acid SCHEMBL7385566 | 0.78 | RAPGEF3 (0.35) | F10F2RAPGEF3PRSS1HPGDS | |
| Trifluoroacetic Acid SCHEMBL7424271 | 0.78 | F10 (0.49) | F10F2 | |
| SCHEMBL7374683 | 0.78 | F10 (0.37) | F10F2RAPGEF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944386-A4 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARM PROD INC (US) | 2001-04-11 | — | — | EP | claimed |
| EP-0944386-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-09-29 | — | — | EP | claimed |
| WO-1998025611-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-06-18 | — | — | WO | claimed |
| EP-0944386-A4 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARM PROD INC (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-0944386-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025611-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-06-18 | — | — | WO | disclosed |