Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.41 |
| ▸ | F10 | P00742 | 4/20 | 0.37 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.35 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | F12 | P00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382013 | 0.85 | F2 (0.36) | F2PRSS1F10RAPGEF3KLK6 | |
| Trifluoroacetic Acid SCHEMBL7384671 | 0.80 | NOS1 (0.37) | F2PRSS1F10RAPGEF3HPGDS | |
| Trifluoroacetic Acid SCHEMBL7374889 | 0.79 | NOS1 (0.46) | F2PRSS1F10RAPGEF3HPGDS | |
| Trifluoroacetic Acid SCHEMBL7385566 | 0.78 | RAPGEF3 (0.35) | F2PRSS1F10RAPGEF3HPGDS | |
| Trifluoroacetic Acid SCHEMBL7541207 | 0.76 | F10 (0.60) | F2PRSS1F10KLK6 | |
| Trifluoroacetic Acid SCHEMBL7375646 | 0.76 | RAPGEF3 (0.35) | F2PRSS1F10RAPGEF3HPGDS | |
| SCHEMBL2364436 | 0.74 | F10 (0.38) | F2PRSS1F10RAPGEF3KLK6 | |
| SCHEMBL7384883 | 0.72 | F10 (0.40) | F2F10RAPGEF3MEN1KMT2A | |
| SCHEMBL7382892 | 0.71 | NCF1 (0.43) | F2PRSS1F10RAPGEF3HPGDS | |
| SCHEMBL7381947 | 0.70 | MEN1 (0.35) | F2F10RAPGEF3HPGDSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944386-A4 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARM PROD INC (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-0944386-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025611-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-06-18 | — | — | WO | disclosed |