SCHEMBL7375304

SCHEMBL7375304

Cc1ccc(N2CN=CN(C)C2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 1/20 0.40
MAPT P10636 6/20 0.35
NPSR1 Q6W5P4 2/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
DHFR P00374 2/20 0.33
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
AKR1C3 P42330 1/20 0.33
F2 P00734 1/20 0.32
ELANE P08246 1/20 0.32
CTSG P08311 1/20 0.32
CMA1 P23946 1/20 0.32
CTRC Q99895 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
NOTUM Q6P988 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4058539 0.88 ADRB1 (0.37) ADRB1MAPTMEN1KMT2ADHFR
SCHEMBL10961523 0.72 LMNA (0.44) MAPTNPSR1MEN1KMT2AHTT
SCHEMBL10805294 0.70 LMNA (0.34) ADRB1MAPTNPSR1HTTSMN1; SMN2
SCHEMBL9678667 0.70 ADRB1 (0.56) ADRB1MAPTNPSR1MEN1KMT2A
SCHEMBL818462 0.66 ADRB1 (0.58) ADRB1MAPTNPSR1MEN1KMT2A
SCHEMBL19526544 0.65
SCHEMBL3414344 0.65 ADRB1 (0.70) ADRB1MAPTNPSR1MEN1KMT2A
SCHEMBL10063748 0.65 ADRB1 (0.70) ADRB1MAPTNPSR1MEN1KMT2A
SCHEMBL7105773 0.65 ADRB1 (0.70) ADRB1MAPTNPSR1MEN1KMT2A
Hydrochloric Acid SCHEMBL7721532 0.65 ADRB1 (0.56) ADRB1MAPTNPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113201804-B Fiber and preparation method thereof 上海邃铸科技有限公司 2023-05-09 CN claimed
CN-113249816-B Transparent fiber and preparation method thereof 上海邃铸科技有限公司 2023-05-05 CN claimed
CN-113201804-B Fiber and preparation method thereof 上海邃铸科技有限公司 2023-05-09 CN disclosed
CN-113249816-B Transparent fiber and preparation method thereof 上海邃铸科技有限公司 2023-05-05 CN disclosed
EP-0787132-A1 BICYCLIC TETRAHYDRO PYRAZOLOPYRIDINES AND THEIR USE AS MEDICAMENTS PFIZER INC. (US) 1997-08-06 EP disclosed
WO-1996012720-A1 BICYCLIC TETRAHYDRO PYRAZOLOPYRIDINES AND THEIR USE AS MEDICAMENTS PFIZER INC. (US) 1996-05-02 WO disclosed
EP-0707585-A1 BICYCLIC TETRAHYDRO PYRAZOLOPYRIDINES PFIZER INC. (US) 1996-04-24 EP disclosed
WO-1995001980-A1 BICYCLIC TETRAHYDRO PYRAZOLOPYRIDINES PFIZER INC. (US) 1995-01-19 WO disclosed
WO-1992002513-A1 HETEROCYCLIC COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-02-20 WO disclosed
US-4273784-A PROSTAGLANDINS WITH CYCLOPROPANE RING IN 2,3 POSITION, OXYTOCICS, ANTISECRETORY, ANTICOAGULANTS, DECONGESTANTS SANDOZ LTD. (CH) 1981-06-16 US disclosed
US-4017492-A As-triazinobenzodiazepin-1-ones THE UPJOHN COMPANY (US) 1977-04-12 US disclosed