Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 5/20 | 0.55 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.52 |
| ▸ | LAP3 | P28838 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8179621 | 0.90 | NPC1 (0.56) | LNPEPLTA4HRENLAP3 | |
| SCHEMBL7698099 | 0.89 | LNPEP (0.59) | BCHELNPEPLTA4HLAP3 | |
| SCHEMBL21919164 | 0.86 | LTA4H (0.57) | LNPEPLTA4HRENLAP3 | |
| SCHEMBL7346203 | 0.83 | CTSS (0.53) | DPP7REN | |
| SCHEMBL5099006 | 0.83 | PDCD1 (0.65) | BCHE | |
| SCHEMBL7375405 | 0.81 | BCHE (0.52) | DPP7BCHE | |
| SCHEMBL27386689 | 0.81 | LTA4H (0.65) | LNPEPLTA4HLAP3 | |
| SCHEMBL7281929 | 0.80 | MMP9 (0.63) | LNPEPLTA4HLAP3 | |
| SCHEMBL7371156 | 0.80 | HTT (0.57) | DPP7LNPEPLTA4H | |
| SCHEMBL3930097 | 0.80 | EPOR (0.57) | LNPEPLTA4HRENLAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117841-A | USED TO TREAT STROKE, CEREBRAL ISCHEMIA, PAIN, HEAD TRAUMA OR EPILEPSY | WARNER-LAMBERT COMPANY (US) | 2000-09-12 | — | — | US | claimed |
| US-6117841-A | USED TO TREAT STROKE, CEREBRAL ISCHEMIA, PAIN, HEAD TRAUMA OR EPILEPSY | WARNER-LAMBERT COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |