Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6800143 | 0.84 | OPRD1 (0.43) | OPRD1OPRK1AGTR2AGTR1ALDH1A1 | |
| SCHEMBL7366919 | 0.82 | CYP19A1 (0.44) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL2570512 | 0.76 | OPRD1 (0.54) | OPRD1OPRK1AGTR2AGTR1ALDH1A1 | |
| SCHEMBL17751291 | 0.75 | CETP (0.52) | ALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL6801299 | 0.70 | RAB9A (0.49) | SMN1; SMN2CYP2C9 | |
| SCHEMBL14258103 | 0.70 | TSHR (0.47) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL27760547 | 0.70 | CYP19A1 (0.51) | — | |
| SCHEMBL6798543 | 0.69 | OPRD1 (0.55) | OPRD1OPRK1AGTR2AGTR1ALDH1A1 | |
| SCHEMBL16830452 | 0.69 | MC4R (0.60) | ALDH1A1 | |
| SCHEMBL15882750 | 0.68 | L3MBTL1 (0.45) | ALDH1A1SMN1; SMN2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073638-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES, THEIR PRODUCTION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054304-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES, THEIR PRODUCTION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-28 | — | — | WO | disclosed |