Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374432 | 0.85 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2KMT2AMEN1CYP2C19 | |
| SCHEMBL7375430 | 0.82 | OPRD1 (0.45) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL6801299 | 0.80 | RAB9A (0.49) | CYP19A1ADRB1ADRB3SMN1; SMN2CYP2C9 | |
| Hydrochloric Acid SCHEMBL10504673 | 0.79 | OPRD1 (0.43) | CYP19A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9022279 | 0.79 | KMT2A (0.45) | CYP19A1ICMTKMT2AMEN1SIGMAR1 | |
| SCHEMBL27760547 | 0.76 | CYP19A1 (0.51) | CYP19A1ADRB1ADRB3KMT2A | |
| SCHEMBL29118370 | 0.74 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1CYP2C19CYP2D6 | |
| SCHEMBL10962884 | 0.74 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8865721 | 0.73 | VDR (0.54) | CYP19A1ADRB1ADRB3ALDH1A1KMT2A | |
| SCHEMBL20570065 | 0.71 | CYP1A2 (0.48) | CYP19A1KMT2ACYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073638-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES, THEIR PRODUCTION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054304-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES, THEIR PRODUCTION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-28 | — | — | WO | disclosed |