Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371580 | 0.85 | MEN1 (0.34) | SLC18A3ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL7371962 | 0.82 | DRD4 (0.34) | ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL7543136 | 0.82 | MEN1 (0.36) | ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL7542970 | 0.76 | CAPN1 (0.36) | ALDH1A1MEN1KMT2ANPSR1CAPN1 | |
| SCHEMBL7370272 | 0.69 | MEN1 (0.54) | ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL5871291 | 0.68 | NPC1 (0.39) | ALDH1A1 | |
| SCHEMBL7366679 | 0.67 | DRD4 (0.63) | — | |
| SCHEMBL27628961 | 0.66 | CYP2C19 (0.40) | ALDH1A1 | |
| SCHEMBL8765520 | 0.64 | SMN1; SMN2 (0.62) | ALDH1A1MEN1KMT2ANPSR1CHRM4 | |
| SCHEMBL27733749 | 0.63 | ALDH1A1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243959-A1 | Substituted benzamide derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-11-04 | — | — | EP | disclosed |