Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485689 | 0.85 | FABP7 (0.42) | ALDH1A1PREPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9180507 | 0.73 | FABP7 (0.40) | ALDH1A1S1PR5PREPNPC1RAB9A | |
| SCHEMBL5871291 | 0.71 | NPC1 (0.39) | ALDH1A1NPC1RAB9ASMN1; SMN2CYP2C19 | |
| SCHEMBL13386604 | 0.69 | ALDH1A1 (0.55) | ALDH1A1 | |
| SCHEMBL6262331 | 0.69 | NPC1 (0.37) | ALDH1A1S1PR5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27739724 | 0.69 | GRM5 (0.36) | ALDH1A1 | |
| SCHEMBL7448545 | 0.68 | SMN1; SMN2 (0.53) | ALDH1A1S1PR5PREPNPC1RAB9A | |
| SCHEMBL29191411 | 0.67 | SMN1; SMN2 (0.49) | ALDH1A1S1PR5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7543136 | 0.67 | MEN1 (0.36) | ALDH1A1PREPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28775111 | 0.67 | ALDH1A1 (0.46) | ALDH1A1PREPNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189222-B | Tri-, tetra-substituted-3-aminopyrrolidine derivative | DAIICHI SANKYO CO LTD | 2013-01-02 | — | — | CN | disclosed |
| CN-101189222-A | Tri-, tetra-substituted-3-aminopyrrolidine derivative | DAIICHI SEIYAKU CO (JP) | 2008-05-28 | — | — | CN | disclosed |