Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371612 | 0.91 | L3MBTL1 (0.42) | THRATHRBATMMCHR1L3MBTL1 | |
| SCHEMBL7372944 | 0.87 | AVPR2 (0.41) | THRBMCHR1MEN1ALDH1A1KMT2A | |
| SCHEMBL7375488 | 0.85 | MCHR1 (0.47) | PPARDMCHR1L3MBTL1LTB4RCNR2 | |
| SCHEMBL7373541 | 0.85 | ALDH1A1 (0.41) | PPARDTHRATHRBMCHR1L3MBTL1 | |
| SCHEMBL7373520 | 0.78 | FABP4 (0.38) | L3MBTL1LTB4RMEN1ALDH1A1KMT2A | |
| SCHEMBL7514175 | 0.76 | MCHR1 (0.38) | THRATHRBMCHR1L3MBTL1ALDH1A1 | |
| SCHEMBL7371273 | 0.76 | MCHR1 (0.46) | MCHR1L3MBTL1 | |
| SCHEMBL7368631 | 0.76 | MCHR1 (0.44) | PPARDMCHR1L3MBTL1MEN1ALDH1A1 | |
| SCHEMBL7377771 | 0.75 | ATM (0.53) | ATML3MBTL1ALDH1A1KMT2AMAPT | |
| SCHEMBL7370294 | 0.74 | HPGD (0.49) | PPARDMCHR1L3MBTL1LTB4RMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |