Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 12/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4152683 | 0.75 | RAB9A (0.42) | PIK3CBALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL938963 | 0.75 | NPC1 (0.42) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL207390 | 0.75 | LMNA (0.44) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL207265 | 0.75 | AHR (0.37) | PIK3CAALDH1A1MAPTALOX15HTT | |
| SCHEMBL7288719 | 0.75 | CA12 (0.39) | ALDH1A1HSD17B10MEN1KMT2ACA12 | |
| SCHEMBL940594 | 0.72 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL3572976 | 0.72 | RAB9A (0.47) | ALDH1A1HPGDMAPTSMN1; SMN2MEN1 | |
| SCHEMBL5337212 | 0.71 | CYP2A6 (0.42) | ALDH1A1KDM4E | |
| SCHEMBL11784689 | 0.71 | RAB9A (0.42) | ALDH1A1KDM4EHPGDMAPTALOX15 | |
| SCHEMBL407727 | 0.71 | PKM (0.45) | KDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164371-A | HETEROCYCLIC KETONES | ICI AMERICAS INC. (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0291234-A2 | Peptidic human leukocyte elastase (HLE) inhibitors | ZENECA INC. (US) | 1988-11-17 | — | — | EP | disclosed |