Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.53 |
| ▸ | MME | P08473 | 2/20 | 0.53 |
| ▸ | ECE1 | P42892 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9069505 | 0.90 | HTT (0.54) | HTT | |
| SCHEMBL10645589 | 0.85 | ACE (0.49) | ACEMMEECE1MMEL1 | |
| SCHEMBL650610 | 0.85 | ACE (0.59) | ACEMMEMMEL1 | |
| SCHEMBL391211 | 0.85 | ACE (0.59) | ACEMMEMMEL1 | |
| SCHEMBL5603448 | 0.85 | ACE (0.59) | ACEMMEMMEL1 | |
| SCHEMBL10420650 | 0.85 | TACR1 (0.57) | ACECTSLCTSBCTSSCTSK | |
| SCHEMBL7382190 | 0.84 | ACE (0.48) | ACEMMEMMEL1 | |
| SCHEMBL7383950 | 0.84 | ACE (0.48) | ACEMMEECE1MMEL1 | |
| SCHEMBL9069258 | 0.84 | CTSS (0.52) | ACEMMECTSLCTSBCTSS | |
| SCHEMBL10651220 | 0.83 | MMEL1 (0.56) | ACEMMEMMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906615-A | Substituted dipeptides as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| US-4721726-A | ANALGESICS | SCHERING CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |
| US-4610816-A | ANALGESICS | SCHERING CORPORATION (US) | 1986-09-09 | — | — | US | disclosed |