Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 2/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 11/20 | 0.47 |
| ▸ | MMP3 | P08254 | 11/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CPA3 | P15088 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385943 | 1.00 | S1PR2 (0.49) | S1PR2S1PR1S1PR3MMP2MMP3 | |
| SCHEMBL7386705 | 0.88 | L3MBTL1 (0.54) | S1PR2S1PR1S1PR3MMP2MMP3 | |
| SCHEMBL7427004 | 0.88 | L3MBTL1 (0.54) | S1PR2S1PR1S1PR3MMP2MMP3 | |
| SCHEMBL7365950 | 0.88 | L3MBTL1 (0.54) | S1PR2S1PR1S1PR3MMP2MMP3 | |
| SCHEMBL7428530 | 0.84 | MMP2 (0.52) | MMP2MMP3 | |
| SCHEMBL7419061 | 0.79 | MMP2 (0.48) | S1PR2S1PR1S1PR3MMP2MMP3 | |
| SCHEMBL7422139 | 0.78 | MMP3 (0.47) | S1PR2S1PR1S1PR3MMP2MMP3 | |
| SCHEMBL21895810 | 0.77 | MMP2 (0.61) | S1PR2S1PR1MMP2MMP3 | |
| SCHEMBL7382744 | 0.77 | MMP2 (0.55) | S1PR2S1PR1S1PR3MMP2MMP3 | |
| SCHEMBL7362919 | 0.77 | MMP2 (0.55) | S1PR2S1PR1S1PR3MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946166-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR TREATING NEUROLOGICAL DISORDERS AND PROMOTING WOUND HEALING | WARNER-LAMBERT COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998026773-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR TREATING NEUROLOGICAL DISORDERS AND PROMOTING WOUND HEALING | WARNER-LAMBERT COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |