Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 18/20 | 0.52 |
| ▸ | MMP3 | P08254 | 18/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382804 | 0.88 | MMP3 (0.58) | MMP2MMP3 | |
| SCHEMBL7382801 | 0.88 | MMP3 (0.58) | MMP2MMP3 | |
| SCHEMBL7385943 | 0.84 | S1PR2 (0.49) | MMP2MMP3 | |
| SCHEMBL7375728 | 0.84 | S1PR2 (0.49) | MMP2MMP3 | |
| SCHEMBL7470292 | 0.79 | MMP2 (0.50) | MMP2MMP3 | |
| SCHEMBL7422973 | 0.78 | MMP2 (0.67) | MMP2MMP3 | |
| SCHEMBL7422976 | 0.78 | MMP2 (0.67) | MMP2MMP3 | |
| SCHEMBL7367245 | 0.76 | MMP2 (0.60) | MMP2MMP3GRIK1 | |
| SCHEMBL21895810 | 0.73 | MMP2 (0.61) | MMP2MMP3 | |
| SCHEMBL7382744 | 0.73 | MMP2 (0.55) | MMP2MMP3GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1063991-A1 | STATIN-MATRIX METALLOPROTEINASE INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY LLC (US) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999047138-A1 | STATIN-MATRIX METALLOPROTEINASE INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-09-23 | — | — | WO | disclosed |