Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 4/20 | 0.32 |
| ▸ | ACE | P12821 | 3/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1028407 | 0.80 | NPC1 (0.32) | HTR2B | |
| Succinic Acid SCHEMBL2849113 | 0.74 | USP5 (0.33) | — | |
| SCHEMBL7375776 | 0.73 | GAA (0.59) | GAAMAPTHTR1AHTR2ADRD3 | |
| SCHEMBL91080 | 0.73 | GAA (1.00) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL1134239 | 0.73 | GAA (1.00) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL29365197 | 0.73 | GAA (1.00) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL14003020 | 0.73 | GAA (1.00) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL29495388 | 0.73 | GAA (1.00) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL926388 | 0.73 | GAA (1.00) | GAAMAPTMMEACESMYD3 | |
| Water SCHEMBL27677887 | 0.72 | GAA (0.90) | GAAMAPTMMEACESMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793674-B1 | HUMAN NEUTROPHIL ELASTASE INHIBITORS | CORTECH INC (US) | 2000-05-24 | — | — | EP | claimed |
| EP-0793674-A1 | HUMAN NEUTROPHIL ELASTASE INHIBITORS | CORTECH, INC. (US) | 1997-09-10 | — | — | EP | claimed |
| WO-1996016080-A1 | HUMAN NEUTROPHIL ELASTASE INHIBITORS | CORTECH, INC. (US) | 1996-05-30 | — | — | WO | claimed |