Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL2849113 | 0.93 | USP5 (0.33) | ALDH1A1POLBRBP4 | |
| SCHEMBL28166840 | 0.86 | PDE4B (0.32) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1898647 | 0.86 | — | — | |
| SCHEMBL10922111 | 0.86 | QDPR (0.40) | ALDH1A1POLBKCNH2 | |
| SCHEMBL28056726 | 0.83 | NPC1 (0.41) | NPC1RAB9AATMHTR2BCA12 | |
| SCHEMBL7375779 | 0.80 | GAA (0.53) | HTR2B | |
| SCHEMBL28056784 | 0.79 | PARP10 (0.46) | NPC1RAB9AATMCA12CA1 | |
| Acetic Acid SCHEMBL1666951 | 0.77 | CHRNB2 (0.30) | — | |
| SCHEMBL28056859 | 0.73 | FDFT1 (0.47) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL28056837 | 0.73 | ABL1 (0.40) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274328-A1 | PEPTIDES, PEPTIDOMIMETICS AND DERIVATIVES THEREOF, THE MANUFACTURING THEREOF AS WELL AS THEIR USE FOR PREPARING A THERAPEUTICALLY AND/OR PREVENTIVELY ACTIVE PHARMACEUTICAL COMPOSITION | Fibrex Medical Research & Development GmbH (AT) | 2011-01-19 | — | — | EP | claimed |
| WO-2009137850-A1 | PEPTIDES, PEPTIDOMIMETICS AND DERIVATIVES THEREOF, THE MANUFACTURING THEREOF AS WELL AS THEIR USE FOR PREPARING A THERAPEUTICALLY AND/OR PREVENTIVELY ACTIVE PHARMACEUTICAL COMPOSITION | FIBREX MEDICAL RESEARCH & DEVELOPMENT GMBH (AT) | 2009-11-19 | — | — | WO | claimed |
| US-20030216324-A1 | Airway mucus secretion inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-11-20 | — | — | US | claimed |
| US-20030212115-A1 | Remedies for inflammatory bowel diseases | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-11-13 | — | — | US | claimed |
| US-20030171539-A1 | Anti-heparin peptides | DIAGNOSTICA-STAGO (FR) | 2003-09-11 | — | — | US | claimed |
| US-6608175-B2 | Oxadiazole, thiadiazoles or triazole metal derivatives reacted with an amine containing aldehyde, deprotecting, coupling with an acid and oxidizing to create substituted oxadiazole, thiadiazole or triazole peptoids | CORTECH, INC. | 2003-08-19 | — | — | US | claimed |
| EP-1323420-A1 | REMEDIES FOR INFLAMMATORY BOWEL DISEASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-07-02 | — | — | EP | claimed |
| EP-1323419-A1 | AIRWAY MUCUS SECRETION INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-07-02 | — | — | EP | claimed |
| EP-1147097-A1 | PEPTIDYL HETEROCYCLIC KETONES USEFUL AS TRYPTASE INHIBITORS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2001-10-24 | — | — | EP | claimed |
| EP-1105412-A1 | SERINE PROTEASE INHIBITORS COMPRISING ALPHA-KETO HETEROCYCLES | CORTECH, INC. (US) | 2001-06-13 | — | — | EP | claimed |
| WO-1998049190-A9 | SUBSTITUTED OXADIAZOLE CYSTEINE PROTEASE INHIBITORS | CORTECH INC (US) | 1999-04-15 | — | — | WO | claimed |
| US-5869455-A | SUBSTITUTED OXADIAZOLE, THIADIAZOLE AND TRIAZOLE PEPTOIDS WHICH ARE USEFUL AS INHIBITORS OF HUMAN NEUTROPHIL ELASTASE | CORTECH, INC. (US) | 1999-02-09 | — | — | US | claimed |
| WO-1998049190-A2 | SUBSTITUTED OXADIAZOLE CYSTEINE PROTEASE INHIBITORS | CORTECH, INC. (US) | 1998-11-05 | — | — | WO | claimed |
| US-5753619-A | CYCLIC HEPTAPEPTIDES FOR CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INSUSTRIES, LTD. (JP) | 1998-05-19 | — | — | US | claimed |
| EP-0833839-A1 | PEPTIDYL HETEROCYCLES USEFUL IN THE TREATMENT OF THROMBIN RELATED DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-04-08 | — | — | EP | claimed |
| US-5618792-A | USEFUL FOR TREATING ACUTE RESPIRATORY DISEASES, AND MYOCARDIAL ISHCEMIA-REPERFUSION INJURY | CORTECH, INC. (US) | 1997-04-08 | — | — | US | claimed |
| WO-1996040742-A1 | PEPTIDYL HETEROCYCLES USEFUL IN THE TREATMENT OF THROMBIN RELATEDDISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-12-19 | — | — | WO | claimed |
| WO-1996040741-A1 | PEPTIDYL HETEROCYCLES USEFUL IN THE TREATMENT OF THROMBIN RELATED DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-12-19 | — | — | WO | claimed |
| WO-1996040748-A1 | PEPTIDYL HETEROCYCLES USEFUL IN THE TREATMENT OF THROMBIN RELATED DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-12-19 | — | — | WO | claimed |
| EP-0714909-A1 | Composition for prophylaxis or treatment of pulmonary circulatory diseases | Takeda Chemical Industries, Ltd. (JP) | 1996-06-05 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212115-A1 | Remedies for inflammatory bowel diseases | NOS3, TPMT, NOS2 | NPC1 3419/4885RAB9A 3973/4885ATM 2585/4885 |
| US-20030171539-A1 | Anti-heparin peptides | SERPINC1, F13B, ZYX | NPC1 3966/4885RAB9A 2503/4885ATM 4054/4885 |
| US-20030216324-A1 | Airway mucus secretion inhibitors | MUC1, CFTR, SERPINB1 | NPC1 1871/4885RAB9A 2939/4885ATM 1083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.