Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7377556 | 0.95 | ALDH1A1 (0.43) | GSRALDH1A1F2PRSS1DPP7 | |
| SCHEMBL7950828 | 0.85 | ALDH1A1 (0.42) | ALDH1A1F2PLA2G4ACES1CTSK | |
| Lysine SCHEMBL358312 | 0.84 | GSR (0.56) | GSRALDH1A1PLA2G4ACES1 | |
| Lysine SCHEMBL1983160 | 0.84 | GSR (0.56) | GSRALDH1A1PLA2G4ACES1 | |
| SCHEMBL358313 | 0.82 | GSR (0.38) | GSRALDH1A1F2PRSS1DPP7 | |
| SCHEMBL8800894 | 0.81 | ALDH1A1 (0.44) | ALDH1A1F2DPP8DPP9PLA2G4A | |
| SCHEMBL7378372 | 0.81 | ALDH1A1 (0.42) | ALDH1A1PLA2G4ACES1CTSK | |
| Hydrochloric Acid SCHEMBL28172161 | 0.81 | PLA2G4A (0.40) | ALDH1A1F2PLA2G4ACES1CTSK | |
| SCHEMBL19630898 | 0.79 | F2 (0.48) | ALDH1A1F2PRSS1CTSKF10 | |
| SCHEMBL27699627 | 0.76 | ALDH1A1 (0.50) | ALDH1A1PLA2G4ACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291678-B1 | CAN BE INCORPORATED IN INHIBITORS OF SERINE PROTEASES WHICH ARE USED IN THERAPY OF ABNORMAL COAGULATION; THERAPY OR PROPHYLAXIS OF SEPTIC SHOCK, ATHEROSCLEROSIS, ALZHEIMER'S AND PARKINSON'S DISEASE | WARNER-LAMBERT COMPANY | 2001-09-18 | — | — | US | disclosed |
| US-6057314-A | ANTICOAGULANTS | BIOCHEM PHARMA INC. (CA) | 2000-05-02 | — | — | US | disclosed |
| EP-0906296-A1 | PROCESS FOR THE PREPARATION OF CHIRAL KETO-HETEROCYCLES OF BASIC AMINO ACIDS | WARNER-LAMBERT COMPANY LLC (US) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997048687-A1 | PROCESS FOR THE PREPARATION OF CHIRAL KETO-HETEROCYCLES OF BASIC AMINO ACIDS | WARNER-LAMBERT COMPANY (US) | 1997-12-24 | — | — | WO | disclosed |
| WO-1996019483-A1 | LOW MOLECULAR WEIGHT BICYCLIC THROMBIN INHIBITORS | BIOCHEM PHARMA INC. (CA) | 1996-06-27 | — | — | WO | disclosed |