Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 10/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313780 | 0.86 | POLB (0.55) | OPRM1OPRD1NPSR1POLBDPP7 | |
| SCHEMBL7313784 | 0.86 | POLB (0.55) | OPRM1OPRD1NPSR1POLBDPP7 | |
| SCHEMBL7374474 | 0.84 | MMP2 (0.47) | SLC6A9SLC6A5TSHRF7 | |
| SCHEMBL7370114 | 0.82 | SLC6A9 (0.49) | OPRD1SLC6A9SLC6A5TSHRF7 | |
| SCHEMBL7371275 | 0.81 | SLC6A9 (0.53) | SLC6A9SLC6A5TSHRF7GPR139 | |
| Hydrochloric Acid SCHEMBL11362510 | 0.79 | OPRD1 (0.63) | OPRM1OPRD1CNR2 | |
| SCHEMBL7372402 | 0.79 | SLC6A9 (0.51) | OPRD1SLC6A9SLC6A5TSHRF7 | |
| SCHEMBL13880547 | 0.77 | SLC6A9 (0.47) | NPSR1POLBSLC6A9SLC6A5TSHR | |
| SCHEMBL8246910 | 0.76 | ATM (0.42) | OPRM1OPRD1NPSR1POLBCNR2 | |
| SCHEMBL8249597 | 0.76 | MMP2 (0.50) | OPRM1OPRD1NPSR1POLBCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994027958-A1 | 4-AMIDINOPHENYLSULPHONAMIDES FOR THE TREATMENT OF THROMBO-EMBOLITIC CONDITIONS | BOEHRINGER MANNHEIM GMBH (DE) | 1994-12-08 | — | — | WO | disclosed |