Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376688 | 0.80 | F2 (0.42) | MAPTALDH1A1KDM4EMAPK1RCE1 | |
| SCHEMBL7775637 | 0.79 | PTGDR2 (0.41) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL7771927 | 0.78 | KDM4E (0.44) | MAPTALDH1A1HTTGAAHPGD | |
| SCHEMBL8125439 | 0.77 | FPR1 (0.39) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL7771925 | 0.77 | LMNA (0.37) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL8107158 | 0.77 | IDH1 (0.39) | THRB | |
| SCHEMBL8111245 | 0.76 | NPSR1 (0.41) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL8123028 | 0.75 | F2 (0.44) | ALDH1A1KMT2ARAB9ALMNA | |
| SCHEMBL7371665 | 0.73 | F2 (0.49) | — | |
| SCHEMBL7771930 | 0.71 | SMN1; SMN2 (0.43) | MAPTALDH1A1HTTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000032574-A1 | NOVEL 2-PYRIDONE DERIVATIVES, PREPARATION METHOD AND THERAPEUTIC USE | SANOFI-SYNTHELABO (FR) | 2000-06-08 | — | — | WO | disclosed |