Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107158 | 0.88 | IDH1 (0.39) | PTGDR2SMN1; SMN2 | |
| SCHEMBL8125439 | 0.82 | FPR1 (0.39) | PTGDR2LMNAHTTMEN1KMT2A | |
| SCHEMBL7376458 | 0.79 | MAPT (0.42) | NPC1LMNAHTTMAPTMEN1 | |
| SCHEMBL7771927 | 0.79 | KDM4E (0.44) | POLBSMN1; SMN2NPC1LMNAHTT | |
| SCHEMBL7771637 | 0.77 | SMN1; SMN2 (0.41) | POLBSMN1; SMN2LMNAHTTMAPT | |
| SCHEMBL7772080 | 0.75 | ALDH1A1 (0.38) | POLBATMSMN1; SMN2NPC1LMNA | |
| SCHEMBL7771925 | 0.75 | LMNA (0.37) | NPC1LMNAHTTMAPTMEN1 | |
| SCHEMBL7767875 | 0.75 | KDM4E (0.43) | POLBSMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL7775674 | 0.75 | TP53 (0.48) | POLBSMN1; SMN2LMNAHTTMAPT | |
| SCHEMBL8123909 | 0.71 | CYP1A2 (0.45) | PTGDR2SMN1; SMN2NPC1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252082-B1 | CARDIOVASCUALR DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-06-26 | — | — | US | disclosed |