Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.36 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773566 | 0.85 | MAPT (0.44) | MEN1KMT2AHTTNPC1ALDH1A1 | |
| SCHEMBL7771930 | 0.79 | SMN1; SMN2 (0.43) | LMNAMEN1KMT2AHTTNPC1 | |
| SCHEMBL7376458 | 0.77 | MAPT (0.42) | LMNAMEN1KMT2AHTTNPC1 | |
| SCHEMBL8111245 | 0.77 | NPSR1 (0.41) | LMNAMEN1KMT2AHTTNPC1 | |
| SCHEMBL8123028 | 0.76 | F2 (0.44) | LMNAKMT2AALDH1A1RAB9A | |
| SCHEMBL7380155 | 0.75 | ALDH1A1 (0.34) | LMNAGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7775637 | 0.75 | PTGDR2 (0.41) | LMNAMEN1KMT2AHTTNPC1 | |
| SCHEMBL20545770 | 0.74 | KDM4E (0.44) | LMNAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7221090 | 0.74 | L3MBTL1 (0.48) | LMNAGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8125439 | 0.73 | FPR1 (0.39) | LMNAMEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252082-B1 | CARDIOVASCUALR DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-06-26 | — | — | US | disclosed |