Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 16/20 | 0.75 |
| ▸ | HSD17B1 | P14061 | 14/20 | 0.75 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796131 | 0.90 | HSD17B2 (0.91) | HSD17B2HSD17B1MTNR1AMTNR1BAPP | |
| SCHEMBL7376311 | 0.82 | HSD17B1 (0.57) | HSD17B2HSD17B1 | |
| SCHEMBL7376601 | 0.81 | HSD17B2 (0.68) | HSD17B2HSD17B1 | |
| SCHEMBL7374140 | 0.81 | HSD17B1 (0.71) | HSD17B2HSD17B1 | |
| SCHEMBL12688055 | 0.80 | HSD17B2 (1.00) | HSD17B2HSD17B1 | |
| SCHEMBL7368760 | 0.79 | HTR3E (0.54) | HSD17B2HSD17B1 | |
| SCHEMBL12687959 | 0.79 | HSD17B2 (0.73) | HSD17B2HSD17B1MTNR1AMTNR1B | |
| SCHEMBL7373511 | 0.78 | KMT2A (0.64) | — | |
| SCHEMBL12495904 | 0.78 | HSD17B2 (0.90) | HSD17B2HSD17B1MTNR1AMTNR1B | |
| SCHEMBL666123 | 0.77 | HSD17B2 (0.66) | HSD17B2HSD17B1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |