Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380393 | 0.85 | PTPN2 (0.68) | MAPTLMNAHTTTDP1KMT2A | |
| Acetic Acid SCHEMBL7374080 | 0.84 | PTPN2 (0.60) | MAPTLMNAKMT2AABL1RIN1 | |
| SCHEMBL8135248 | 0.84 | MAPT (0.60) | MAPTLMNAHTTTDP1KMT2A | |
| SCHEMBL8147771 | 0.83 | MAPT (0.59) | MAPTLMNAHTTTDP1KMT2A | |
| SCHEMBL8147769 | 0.83 | MAPT (0.59) | MAPTLMNAHTTTDP1KMT2A | |
| Acetic Acid SCHEMBL7374818 | 0.80 | ALDH1A1 (0.55) | MAPTKMT2AGAAKDM4EABL1 | |
| SCHEMBL8135054 | 0.80 | LMNA (0.49) | MAPTLMNAHTTTDP1KMT2A | |
| SCHEMBL7405463 | 0.80 | ALDH1A1 (0.50) | MAPTKMT2AABL1MAPK1ALDH1A1 | |
| Acetic Acid SCHEMBL7376666 | 0.79 | RAB9A (0.53) | MAPTKMT2AGAAABL1ALDH1A1 | |
| SCHEMBL533096 | 0.78 | ALDH1A1 (0.62) | MAPTLMNAKMT2AGAAABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069143-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0885213-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0885213-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997025323-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-17 | — | — | WO | disclosed |