Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ME3 | Q16798 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | RHOC | P08134 | 1/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7376283 | 0.83 | ME3 (0.50) | ALDH1A1MEN1MAPTKMT2AME3 | |
| SCHEMBL7372038 | 0.81 | PTPN2 (0.67) | ALDH1A1MEN1MAPTKMT2AABL1 | |
| Acetic Acid SCHEMBL7412643 | 0.81 | ME3 (0.48) | ALDH1A1MEN1MAPTKMT2AME3 | |
| SCHEMBL533096 | 0.80 | ALDH1A1 (0.62) | ALDH1A1MEN1MAPTKMT2AME3 | |
| SCHEMBL7376708 | 0.80 | MAPT (0.60) | ALDH1A1MAPTKMT2AABL1MAPK1 | |
| Acetic Acid SCHEMBL7374080 | 0.79 | PTPN2 (0.60) | ALDH1A1MEN1MAPTKMT2AABL1 | |
| Acetic Acid SCHEMBL7374818 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MEN1MAPTKMT2AME3 | |
| Acetic Acid SCHEMBL7376666 | 0.79 | RAB9A (0.53) | ALDH1A1MEN1MAPTKMT2AME3 | |
| SCHEMBL8383393 | 0.79 | MAPT (0.52) | ALDH1A1MEN1MAPTKMT2AME3 | |
| SCHEMBL14624172 | 0.77 | DRD2 (0.53) | ALDH1A1MEN1MAPTKMT2AME3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069143-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0885213-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0885213-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997025323-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-17 | — | — | WO | disclosed |