Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4424459 | 0.89 | MMP2 (0.45) | MMP2MMP9MMP7MMP3MMP12 | |
| SCHEMBL6803242 | 0.89 | NPSR1 (0.43) | MMP2MMP9ANPEPALOX5MMP7 | |
| SCHEMBL6798658 | 0.88 | ALOX5 (0.38) | MMP2MMP9ANPEPRNPEPDNPEP | |
| SCHEMBL6804726 | 0.88 | HSD17B10 (0.39) | MMP2ALOX5MMP7MMP3HPGD | |
| SCHEMBL6801586 | 0.86 | CAPN1 (0.36) | MMP2ANPEPALOX5MMP7MMP3 | |
| SCHEMBL4428169 | 0.80 | NPSR1 (0.43) | MMP2MMP9ANPEPMMP7MMP3 | |
| SCHEMBL4431971 | 0.79 | CTSB (0.42) | MMP2MMP9MMP7MMP3MMP12 | |
| SCHEMBL4421716 | 0.79 | MMP8 (0.42) | MMP2MMP9MMP7MMP3MMP12 | |
| SCHEMBL4431902 | 0.79 | MMP2 (0.39) | MMP2MMP9MMP7MMP3MMP12 | |
| SCHEMBL4425332 | 0.79 | MMP2 (0.39) | MMP2MMP9MMP7MMP3MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1062202-A1 | CYTOSTATIC AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-12-27 | — | — | EP | disclosed |
| WO-1999046241-A1 | CYTOSTATIC AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-09-16 | — | — | WO | disclosed |
| EP-0925278-A1 | CYTOSTATIC HYDROXAMIC ACID DERIVATIVES | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998011063-A1 | CYTOSTATIC HYDROXAMIC ACID DERIVATIVES | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-03-19 | — | — | WO | disclosed |