Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 16/20 | 0.72 |
| ▸ | MMP3 | P08254 | 15/20 | 0.72 |
| ▸ | MMP7 | P09237 | 15/20 | 0.72 |
| ▸ | MMP1 | P03956 | 12/20 | 0.71 |
| ▸ | MMP8 | P22894 | 2/20 | 0.71 |
| ▸ | MMP9 | P14780 | 2/20 | 0.71 |
| ▸ | MMP12 | P39900 | 2/20 | 0.71 |
| ▸ | MMP13 | P45452 | 2/20 | 0.71 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.71 |
| ▸ | MMP14 | P50281 | 1/20 | 0.71 |
| ▸ | ACE | P12821 | 1/20 | 0.57 |
| ▸ | FCER2 | P06734 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4424468 | 0.92 | MMP2 (0.86) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL7651206 | 0.91 | MMP2 (0.67) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL7651203 | 0.91 | MMP2 (0.67) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL6803244 | 0.91 | MMP2 (0.67) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL6804731 | 0.89 | MMP2 (0.66) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL6797912 | 0.89 | MMP2 (0.65) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL6801553 | 0.87 | MMP3 (0.63) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL6801588 | 0.86 | MMP2 (0.62) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL7654835 | 0.84 | MMP2 (0.59) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL15222244 | 0.83 | ACE (0.66) | MMP2MMP3MMP7MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1062202-A1 | CYTOSTATIC AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-12-27 | — | — | EP | disclosed |
| WO-1999046241-A1 | CYTOSTATIC AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-09-16 | — | — | WO | disclosed |
| EP-0925278-A1 | CYTOSTATIC HYDROXAMIC ACID DERIVATIVES | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998011063-A1 | CYTOSTATIC HYDROXAMIC ACID DERIVATIVES | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-03-19 | — | — | WO | disclosed |