SCHEMBL6797912

SCHEMBL6797912

C=CC[C@H](C(=O)O)[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC(C)C

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 16/20 0.65
MMP3 P08254 16/20 0.65
MMP7 P09237 14/20 0.65
MMP1 P03956 15/20 0.64
MMP8 P22894 2/20 0.64
ADAM17 P78536 1/20 0.64
MMP9 P14780 1/20 0.64
MMP12 P39900 1/20 0.64
MMP13 P45452 1/20 0.64
MMP14 P50281 1/20 0.64
FCER2 P06734 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4431907 0.92 MMP2 (0.78) MMP2MMP3MMP7MMP1MMP8
SCHEMBL4425335 0.92 MMP2 (0.78) MMP2MMP3MMP7MMP1MMP8
SCHEMBL6803244 0.92 MMP2 (0.67) MMP2MMP3MMP7MMP1MMP8
SCHEMBL7651203 0.92 MMP2 (0.67) MMP2MMP3MMP7MMP1MMP8
SCHEMBL7651206 0.92 MMP2 (0.67) MMP2MMP3MMP7MMP1MMP8
SCHEMBL6804731 0.90 MMP2 (0.66) MMP2MMP3MMP7MMP1MMP8
SCHEMBL6804212 0.89 MMP2 (0.60) MMP2MMP3MMP7MMP1MMP8
SCHEMBL7376771 0.89 MMP2 (0.72) MMP2MMP3MMP7MMP1MMP8
SCHEMBL6801553 0.88 MMP3 (0.63) MMP2MMP3MMP7MMP1MMP8
SCHEMBL6801588 0.87 MMP2 (0.62) MMP2MMP3MMP7MMP1MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104955332-A Method for controlling arthropod pest SUMITOMO CHEMICAL CO 2015-09-30 CN disclosed
CN-104105694-A Amide compound and use thereof for pest control SUMITOMO CHEMICAL CO 2014-10-15 CN disclosed
US-6790834-B1 Cytostatic agents BRITISH BIOTECH PHARMACEUTICALS, LTD. (GB) 2004-09-14 US disclosed
US-20040110665-A1 Desleucyl glycopeptide antibiotics and methods of making same KAHNE DANIEL (US) 2004-06-10 US disclosed
EP-1062202-B1 CYTOSTATIC AGENTS BRITISH BIOTECH PHARM (GB) 2003-01-15 EP disclosed
US-6462023-B1 SUCH AS 2-HYDROXY-HYDROXYCARBAMOYL-METHYL)-4-METHYL-PENTANOYLAMINE)-2-PHENYL -ETHANOIC ACID CYCLOPENTYL ESTER; INHIBITING HYPERPROLIFERATIVE TUMOURGENIC CELLS SUCH AS MELANOMA AND/OR LYMPHOMA CELLS BRITISH BIOTECH PHARMACEUTICALS, LTD. (GB) 2002-10-08 US disclosed
EP-0925278-B1 CYTOSTATIC HYDROXAMIC ACID DERIVATIVES BRITISH BIOTECH PHARM (GB) 2002-07-17 EP disclosed
CN-1071334-C Glycopeptide antibiotic derivatives LILLY CO ELI (US) 2001-09-19 CN disclosed
US-6169075-B1 ANTITUMOR AGENT INHIBITING THE PROLIFERATION OF A RANGE OF RAPIDLY DIVIDING TUMOUR CELLS LIKE MELANOMA AND/OR LYMPHOMA CELLS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2001-01-02 US disclosed
EP-1062202-A1 CYTOSTATIC AGENTS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2000-12-27 EP disclosed
WO-1999046241-A1 CYTOSTATIC AGENTS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1999-09-16 WO disclosed
EP-0925278-A1 CYTOSTATIC HYDROXAMIC ACID DERIVATIVES BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1999-06-30 EP disclosed
WO-1998011063-A1 CYTOSTATIC HYDROXAMIC ACID DERIVATIVES BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1998-03-19 WO disclosed
CN-1119649-A Glycopeptide antibiotic derivatives LILLY CO ELI (US) 1996-04-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110665-A1 Desleucyl glycopeptide antibiotics and methods of making same FUT6, FUT5, ST6GAL1 MMP2 1331/4885MMP3 2460/4885MMP7 528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.