Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 15/20 | 0.67 |
| ▸ | MMP3 | P08254 | 15/20 | 0.67 |
| ▸ | MMP7 | P09237 | 14/20 | 0.67 |
| ▸ | MMP1 | P03956 | 13/20 | 0.66 |
| ▸ | MMP8 | P22894 | 2/20 | 0.66 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.66 |
| ▸ | MMP9 | P14780 | 1/20 | 0.66 |
| ▸ | MMP12 | P39900 | 1/20 | 0.66 |
| ▸ | MMP13 | P45452 | 1/20 | 0.66 |
| ▸ | MMP14 | P50281 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803244 | 1.00 | MMP2 (0.67) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL7651203 | 1.00 | MMP2 (0.67) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL4428170 | 0.92 | MMP2 (0.81) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL6804731 | 0.92 | MMP2 (0.66) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL6797912 | 0.92 | MMP2 (0.65) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL7376771 | 0.91 | MMP2 (0.72) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL6801588 | 0.91 | MMP2 (0.62) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL6801553 | 0.90 | MMP3 (0.63) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL6808424 | 0.89 | MMP2 (0.62) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL7654835 | 0.86 | MMP2 (0.59) | MMP2MMP3MMP7MMP1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462023-B1 | SUCH AS 2-HYDROXY-HYDROXYCARBAMOYL-METHYL)-4-METHYL-PENTANOYLAMINE)-2-PHENYL -ETHANOIC ACID CYCLOPENTYL ESTER; INHIBITING HYPERPROLIFERATIVE TUMOURGENIC CELLS SUCH AS MELANOMA AND/OR LYMPHOMA CELLS | BRITISH BIOTECH PHARMACEUTICALS, LTD. (GB) | 2002-10-08 | — | — | US | disclosed |