Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375025 | 0.87 | HTR1A (0.40) | ALDH1A1MEN1KMT2AHTR1AHTR1D | |
| SCHEMBL7335732 | 0.87 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL7371731 | 0.86 | KDM4E (0.51) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL7377107 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2ATDP1HTT | |
| SCHEMBL7376935 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL7373593 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL7476833 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2ALMNAHTT | |
| SCHEMBL7345680 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL7374169 | 0.79 | AVPR2 (0.44) | — | |
| SCHEMBL7334833 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |