Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 6/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372971 | 0.86 | NPY5R (0.41) | NPY5RCYP2A6CYP2E1CYP3A4CYP2C9 | |
| SCHEMBL7375478 | 0.84 | CYP11B1 (0.43) | NPY5RCYP2A6CYP2E1CYP3A4CYP2C9 | |
| SCHEMBL28763036 | 0.75 | NPY5R (0.74) | NPY5RCYP3A4CYP2C19KDM4ENPC1 | |
| Fr-79620 SCHEMBL7370865 | 0.74 | NPY5R (1.00) | NPY5RCYP2A6KDM4ENPC1MAPT | |
| SCHEMBL7371445 | 0.73 | NPY5R (0.67) | NPY5RMAPTNPSR1L3MBTL1SMPD3 | |
| SCHEMBL9634600 | 0.73 | PDE5A (0.40) | KDM4ENPC1RAB9AKIT | |
| SCHEMBL27674585 | 0.73 | NPY5R (0.67) | NPY5RCYP3A4CYP2C9CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL9838295 | 0.72 | PDE5A (0.41) | KDM4ENPC1RAB9AKIT | |
| SCHEMBL7371145 | 0.72 | NPY5R (0.65) | NPY5RKDM4ELMNAMAPTNPSR1 | |
| SCHEMBL7367119 | 0.72 | MAPK14 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |