Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 8/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.39 |
| ▸ | RAF1 | P04049 | 6/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | TEK | Q02763 | 3/20 | 0.38 |
| ▸ | GCGR | P47871 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375478 | 0.87 | CYP11B1 (0.43) | RAF1 | |
| SCHEMBL7372687 | 0.79 | MAPK13 (0.39) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL9634600 | 0.78 | PDE5A (0.40) | — | |
| Hydrochloric Acid SCHEMBL9838295 | 0.77 | PDE5A (0.41) | — | |
| SCHEMBL19868943 | 0.73 | MAPK14 (0.67) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL7377115 | 0.72 | NPY5R (0.57) | — | |
| SCHEMBL10739483 | 0.70 | METAP2 (0.39) | — | |
| SCHEMBL10917045 | 0.70 | AMY1A (0.33) | — | |
| Hydrochloric Acid SCHEMBL10743666 | 0.69 | AMY1A (0.33) | — | |
| SCHEMBL7372971 | 0.68 | NPY5R (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |