Fr-79620

Fr-79620

SCHEMBL7370865

Cc1[nH]c(-c2ccccc2)nc1-c1cccnc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 5/20 1.00
HPGDS O60760 1/20 0.63
KDM4E B2RXH2 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
LDHA P00338 1/20 0.50
EPHX2 P34913 1/20 0.50
KMT2A Q03164 1/20 0.50
CYP19A1 P11511 1/20 0.49
SMPD3 Q9NY59 1/20 0.49
HPGD P15428 2/20 0.49
ALDH1A1 P00352 2/20 0.48
NPC1 O15118 1/20 0.48
MAPT P10636 1/20 0.48
STAT1 P42224 1/20 0.48
RAB9A P51151 1/20 0.48
MAPK13 O15264 1/20 0.47
RAF1 P04049 1/20 0.47
MAPK9 P45984 1/20 0.47
MAPK12 P53778 1/20 0.47
MAPK11 Q15759 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28402826 0.94 NPY5R (0.88) NPY5RHPGDSKDM4ESMN1; SMN2LDHA
SCHEMBL2840665 0.86 NPY5R (0.75) NPY5RHPGDSKDM4ESMN1; SMN2LDHA
SCHEMBL2319610 0.86 HPGDS (0.79) NPY5RHPGDSKDM4ESMN1; SMN2LDHA
SCHEMBL28763036 0.86 NPY5R (0.74) NPY5RHPGDSKDM4ESMN1; SMN2CYP19A1
SCHEMBL724250 0.84 NPY5R (0.72) NPY5RHPGDSKDM4ESMN1; SMN2KMT2A
SCHEMBL28399047 0.83 NPY5R (0.71) NPY5RHPGDSSMPD3MAPK13RAF1
SCHEMBL2689052 0.81 NPY5R (0.69) NPY5RKDM4ESMN1; SMN2LDHAEPHX2
SCHEMBL2313376 0.81 NPY5R (0.67) NPY5RHPGDSKDM4ESMN1; SMN2LDHA
SCHEMBL31305589 0.81 NPY5R (0.68) NPY5RHPGDSKDM4EKMT2ASMPD3
SCHEMBL28402852 0.81 NPY5R (0.82) NPY5RHPGDSKDM4ESMN1; SMN2LDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260077012-A1 COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF NEURODEGENERATIVE DISEASES EPITRACKER INC (US) 2026-03-19 US disclosed
US-12427179-B2 Compositions and methods for diagnosis and treatment of neurodegenerative diseases Epitracker, Inc. (US) 2025-09-30 US disclosed
EP-4590287-A1 COMPOSITIONS AND METHODS FOR IMPROVING GUT PERMEABILITY Brightseed, Inc. (US) 2025-07-30 EP disclosed
US-20250205182-A1 COMPOSITIONS AND METHODS FOR IMPROVING GUT PERMEABILITY BRIGHTSEED, INC. 2025-06-26 US disclosed
US-20250000804-A1 COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISORDERS ANJI PHARMA (US) LLC 2025-01-02 US disclosed
US-20240307336-A1 COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF CONDITIONS RELATED TO THE QUALITY OF AGING AND LONGEVITY EPITRACKER INC (US) 2024-09-19 US disclosed
US-20240277649-A1 FATTY ACID ANALOGS AND THEIR USE IN THE TREATMENT OF CONDITIONS RELATED TO METABOLIC SYNDROME EPITRACKER INC (US) 2024-08-22 US disclosed
EP-4410285-A2 COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF METABOLIC SYNDROME Government Of The United States Of America As Represented By The Secretary Of the Navy (US) 2024-08-07 EP disclosed
EP-4410380-A2 DELAYED-RELEASE COMPOSITION COMPRISING BIGUANIDE Anji Pharmaceuticals Inc. (US) 2024-08-07 EP disclosed
US-11992473-B2 Compositions and methods for diagnosis and treatment of conditions related to the quality of aging and longevity Epitracker, Inc. (US) 2024-05-28 US disclosed
US-20230293491-A1 COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF CONDITIONS RELATED TO THE QUALITY OF AGING AND LONGEVITY EPITRACKER INC (US) 2023-09-21 US disclosed
US-11759441-B2 Biguanide compositions and methods of treating metabolic disorders ANJI PHARMACEUTICALS INC. (US) 2023-09-19 US disclosed
US-20230285330-A9 COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISORDERS ANJI PHARMACEUTICALS INC. 2023-09-14 US disclosed
EP-4234038-A2 COMPOSITIONS COMPRISING HEPTADECANOIC ACID FOR THE TREATMENT OF INFLAMMATION AND RELATED CONDITIONS The United States Of America As Represented By The Secretary Of The Navy (US) 2023-08-30 EP disclosed
EP-3562480-B1 COMPOSITIONS COMPRISING HEPTADECANOIC ACID FOR THE TREATMENT OF INFLAMMATION AND RELATED CONDITIONS US NAVY (US) 2023-05-03 EP disclosed
US-20220151957-A1 BIGUANIDE COMPOSITIONS AND METHODS OF TREATING METABOLIC DISORDERS ANJI PHARMACEUTICALS INC. 2022-05-19 US disclosed
WO-2022098572-A1 COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF CONDITIONS RELATED TO THE QUALITY OF AGING AND LONGEVITY Epitracker, Inc. (US) 2022-05-12 WO disclosed
US-4822805-A ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-04-18 US disclosed
CN-87105680-A Imidazolium compounds and preparation method thereof and comprise the pharmaceutical composition of this compound 1988-04-27 CN disclosed
EP-0257897-A1 Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260077012-A1 COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF NEURODEGENERATIVE DISEASES CD4, COL2A1, MMP1 NPY5R 2898/4885HPGDS 51/4885KDM4E 4710/4885
US-20230293491-A1 COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF CONDITIONS RELATED TO THE QUALITY OF AGING AND LONGEVITY BHMT, FTH1, HBG1 NPY5R 1109/4885HPGDS 257/4885KDM4E 4417/4885
US-20250000804-A1 COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISORDERS SLC5A2, SLC10A1, GPR119 NPY5R 912/4885HPGDS 1138/4885KDM4E 3240/4885
US-20250205182-A1 COMPOSITIONS AND METHODS FOR IMPROVING GUT PERMEABILITY FABP2, VIP, SI NPY5R 528/4885HPGDS 174/4885KDM4E 4072/4885
US-11759441-B2 Biguanide compositions and methods of treating metabolic disorders SLC5A2, SLC5A1, GPR119 NPY5R 723/4885HPGDS 2156/4885KDM4E 2303/4885
US-20220151957-A1 BIGUANIDE COMPOSITIONS AND METHODS OF TREATING METABOLIC DISORDERS SLC5A2, SLC5A1, GPR119 NPY5R 723/4885HPGDS 2156/4885KDM4E 2303/4885
US-20240277649-A1 FATTY ACID ANALOGS AND THEIR USE IN THE TREATMENT OF CONDITIONS RELATED TO METABOLIC SYNDROME FABP1, FASN, GPR119 NPY5R 715/4885HPGDS 191/4885KDM4E 3869/4885
US-20230285330-A9 COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISORDERS FABP2, GPR119, PNLIP NPY5R 2671/4885HPGDS 1333/4885KDM4E 3369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.