Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 3/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Threonine SCHEMBL7376382 | 0.91 | GGT1 (0.46) | GGT1MMEACETSHRNAALAD2 | |
| Alanine SCHEMBL7382718 | 0.91 | GGT1 (0.50) | GGT1MMEACETSHRNAALAD2 | |
| Isoleucine SCHEMBL7380261 | 0.89 | GGT1 (0.44) | GGT1MMEACETSHRNAALAD2 | |
| SCHEMBL6423726 | 0.88 | GGT1 (0.57) | GGT1MMEACENAALAD2KEAP1 | |
| Homophenylalanine SCHEMBL7383933 | 0.86 | GGT1 (0.50) | GGT1MMEACENAALAD2KEAP1 | |
| Leucine SCHEMBL6415294 | 0.85 | LTA4H (0.46) | GGT1MMELMNAPKMMMP3 | |
| Glutamic Acid SCHEMBL7375280 | 0.85 | GGT1 (0.49) | GGT1MMEACENAALAD2KEAP1 | |
| Serine SCHEMBL7384366 | 0.84 | GGT1 (0.48) | GGT1MMEACENAALAD2KEAP1 | |
| Phenylalanine SCHEMBL7432097 | 0.84 | ALPI (0.56) | GGT1MMEACENAALAD2KEAP1 | |
| SCHEMBL7383218 | 0.82 | GGT1 (0.53) | GGT1MMEACETSHRNAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1063991-A1 | STATIN-MATRIX METALLOPROTEINASE INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY LLC (US) | 2001-01-03 | — | — | EP | disclosed |
| EP-0946166-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR TREATING NEUROLOGICAL DISORDERS AND PROMOTING WOUND HEALING | WARNER-LAMBERT COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1999047138-A1 | STATIN-MATRIX METALLOPROTEINASE INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-09-23 | — | — | WO | disclosed |
| WO-1998026773-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR TREATING NEUROLOGICAL DISORDERS AND PROMOTING WOUND HEALING | WARNER-LAMBERT COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |