Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 3/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL7377141 | 0.89 | GGT1 (0.47) | GGT1ACEMMESMN1; SMN2TSHR | |
| Threonine SCHEMBL7376382 | 0.88 | GGT1 (0.46) | GGT1ACEMMETSHRNAALAD2 | |
| Alanine SCHEMBL7382718 | 0.88 | GGT1 (0.50) | GGT1ACEMMESMN1; SMN2TSHR | |
| SCHEMBL6423726 | 0.85 | GGT1 (0.57) | GGT1ACEMMESMN1; SMN2NAALAD2 | |
| Homophenylalanine SCHEMBL7383933 | 0.83 | GGT1 (0.50) | GGT1ACEMMESMN1; SMN2NAALAD2 | |
| Leucine SCHEMBL6415294 | 0.82 | LTA4H (0.46) | GGT1MME | |
| Isoleucine SCHEMBL6416482 | 0.82 | MME (0.49) | ACEMME | |
| Glutamic Acid SCHEMBL7375280 | 0.82 | GGT1 (0.49) | GGT1ACEMMENAALAD2 | |
| Norleucine SCHEMBL7430731 | 0.81 | NOD1 (0.48) | GGT1MMES1PR2S1PR1S1PR3 | |
| Serine SCHEMBL7384366 | 0.81 | GGT1 (0.48) | GGT1ACEMMESMN1; SMN2NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1063991-A1 | STATIN-MATRIX METALLOPROTEINASE INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY LLC (US) | 2001-01-03 | — | — | EP | disclosed |
| EP-1047450-A1 | ACE INHIBITOR-MMP INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 2000-11-02 | — | — | EP | disclosed |
| EP-0946166-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR TREATING NEUROLOGICAL DISORDERS AND PROMOTING WOUND HEALING | WARNER-LAMBERT COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1999047138-A1 | STATIN-MATRIX METALLOPROTEINASE INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-09-23 | — | — | WO | disclosed |
| WO-1999032150-A1 | ACE INHIBITOR-MMP INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |
| WO-1998026773-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR TREATING NEUROLOGICAL DISORDERS AND PROMOTING WOUND HEALING | WARNER-LAMBERT COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |