Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 6/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466483 | 0.89 | NPC1 (0.45) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7466500 | 0.81 | ITGB3 (0.40) | SLC7A5ITGB3ITGB1ITGAVITGA2B | |
| SCHEMBL7466505 | 0.81 | ITGB3 (0.40) | SLC7A5ITGB3ITGB1ITGAVITGA2B | |
| SCHEMBL7380737 | 0.80 | MAPT (0.42) | NPC1MAPTHTTRAB9ASMN1; SMN2 | |
| SCHEMBL7375593 | 0.80 | ALDH1A1 (0.42) | ITGB3ITGA2BF10PRSS1F2 | |
| SCHEMBL7382269 | 0.78 | NR1H4 (0.41) | ITGB3ITGAVITGA2BF10PRSS1 | |
| SCHEMBL7409600 | 0.77 | MAPT (0.42) | NPC1MAPTHTTRAB9ASMN1; SMN2 | |
| SCHEMBL7410381 | 0.77 | ITGB3 (0.41) | SLC7A5ITGB3ITGB1ITGAVITGA2B | |
| SCHEMBL7410551 | 0.77 | ITGB3 (0.41) | SLC7A5ITGB3ITGB1ITGAVITGA2B | |
| SCHEMBL7380572 | 0.74 | ITGB3 (0.40) | SLC7A5ITGB3ITGAVITGA2BF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891325-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1997036859-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | claimed |