Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368736 | 0.86 | KMT2A (0.46) | TBXAS1ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL7340316 | 0.85 | MAPT (0.40) | TBXAS1ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL7373263 | 0.85 | TBXAS1 (0.41) | TBXAS1ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL7778250 | 0.80 | RAB9A (0.39) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL7376764 | 0.79 | PPARG (0.42) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL7369617 | 0.79 | TBXAS1 (0.47) | TBXAS1ALDH1A1TDP1LMNACYP1A2 | |
| SCHEMBL7378207 | 0.78 | PTGDR2 (0.41) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL7370181 | 0.75 | L3MBTL1 (0.38) | TBXAS1ALDH1A1TDP1LMNACYP1A2 | |
| SCHEMBL7374555 | 0.73 | USP2 (0.45) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL16147216 | 0.72 | TBXAS1 (0.46) | TBXAS1ALDH1A1TDP1CYP3A4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |