Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 10/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 10/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 10/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 10/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 10/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 10/20 | 0.39 |
| ▸ | FPR3 | P25089 | 3/20 | 0.38 |
| ▸ | FPR2 | P25090 | 3/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410116 | 0.82 | HSPA5 (0.51) | FFAR2MEN1ALDH1A1KMT2A | |
| SCHEMBL7402956 | 0.81 | POLB (0.45) | SMN1; SMN2MEN1ALDH1A1TP53MAPT | |
| SCHEMBL7367564 | 0.80 | FFAR2 (0.39) | FFAR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7370348 | 0.77 | MMP2 (0.46) | FFAR2SMN1; SMN2MAPK1HTT | |
| SCHEMBL7410121 | 0.77 | MMP2 (0.47) | SMN1; SMN2TP53MAPTNPSR1 | |
| SCHEMBL7373809 | 0.77 | MMP1 (0.56) | FFAR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL7371393 | 0.76 | RAB9A (0.43) | FFAR2FPR2SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL6435917 | 0.75 | POLB (0.38) | — | |
| SCHEMBL8777490 | 0.75 | POLB (0.38) | — | |
| SCHEMBL7513209 | 0.75 | MMP1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740652-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1998-05-06 | — | — | EP | claimed |
| EP-0740652-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-11-06 | — | — | EP | claimed |
| WO-1995019956-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-07-27 | — | — | WO | claimed |
| US-5919940-A | TERT-LEUCINE-THIAZOL-2-YLAMIDE | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| US-5859253-A | L-TERT-LEUCINE-2-PYRIDYLAMIDE | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| EP-0740652-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1998-05-06 | — | — | EP | disclosed |
| US-5747514-A | Metalloproteinase inhibitors | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-05-05 | — | — | US | disclosed |
| EP-0740652-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995019956-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-07-27 | — | — | WO | disclosed |