Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3691922 | 0.80 | MAOA (0.44) | MAOAMAOBACHEMTNR1AMTNR1B | |
| SCHEMBL7612685 | 0.79 | PNMT (0.38) | PTGS2MTNR1AMTNR1BDRD2DRD4 | |
| SCHEMBL30018454 | 0.78 | PTGS2 (0.41) | MAOAMAOBACHEPTGS2CYP11B2 | |
| SCHEMBL4652068 | 0.78 | PTGS2 (0.41) | MAOAMAOBACHEPTGS2CYP11B2 | |
| SCHEMBL1577597 | 0.78 | PTGS2 (0.41) | MAOAMAOBACHEPTGS2CYP11B2 | |
| Hydrochloric Acid SCHEMBL7609317 | 0.78 | PNMT (0.38) | PTGS2MTNR1AMTNR1BDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7610603 | 0.78 | PNMT (0.38) | PTGS2MTNR1AMTNR1BDRD2DRD4 | |
| SCHEMBL9272850 | 0.77 | DPP8 (0.32) | HTR2A | |
| SCHEMBL9075944 | 0.76 | CYP3A4 (0.34) | — | |
| SCHEMBL27587040 | 0.76 | PTGS2 (0.40) | MAOAMAOBACHEPTGS2CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038315-B1 | PROCESS FOR PREPARING POLYMERS FROM 3-METHYLBUT-1-ENE | EVONIK DEGUSSA GMBH (DE) | 2013-10-23 | — | — | EP | disclosed |
| US-8202959-B2 | Process for preparing polymers from 3-methylbut-1-ene | EVONIK OXENO GMBH (DE) | 2012-06-19 | — | — | US | disclosed |
| US-8138293-B2 | Process for preparing polymers from 3-methylbut-1-ene | EVONIK OXENO GMBH (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20110201767-A1 | PROCESS FOR PREPARING POLYMERS FROM 3-METHYLBUT-1-ENE | EVONIK OXENO GMBH (DE) | 2011-08-18 | — | — | US | disclosed |
| US-20090203858-A1 | PROCESS FOR PREPARING POLYMERS FROM 3-METHYLBUT-1-ENE | EVONIK OXENO GMBH (DE) | 2009-08-13 | — | — | US | disclosed |
| US-5612462-A | Process for preparing bridged stereorigid metallocenes | WITCO GMBH (DE) | 1997-03-18 | — | — | US | disclosed |
| US-5545785-A | Process for preparing biscyclopentadienyl compounds | WITCO GMBH (DE) | 1996-08-13 | — | — | US | disclosed |
| US-5543535-A | Organotin compounds useful in preparing bridged stereorigid metallocenes | WITCO GMBH (DE) | 1996-08-06 | — | — | US | disclosed |
| US-5474716-A | Process for the preparation of bridged cyclopentadienylmagnesium compounds and use thereof for preparing metallocenes | WITCO GMBH (DE) | 1995-12-12 | — | — | US | disclosed |
| US-5453221-A | Bridged cyclopentadienylmagnesium compounds and use thereof for preparing metallocenes | WITCO GMBH (DE) | 1995-09-26 | — | — | US | disclosed |