Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30018454 | 1.00 | PTGS2 (0.41) | PTGS2MAOAMAOBACHECYP11B2 | |
| Hydrochloric Acid SCHEMBL8317645 | 0.96 | CYP11B2 (0.39) | PTGS2MAOAMAOBACHECYP11B2 | |
| SCHEMBL4652068 | 0.87 | PTGS2 (0.41) | PTGS2MAOAMAOBACHECYP11B2 | |
| SCHEMBL18538825 | 0.83 | MAOA (0.41) | PTGS2MAOAMAOBACHECYP11B2 | |
| SCHEMBL5668053 | 0.83 | PTGS2 (0.39) | PTGS2MAOAMAOBACHECYP11B2 | |
| SCHEMBL4541862 | 0.83 | HTR2A (0.40) | PTGS2MAOAMAOBACHECYP11B2 | |
| SCHEMBL28476230 | 0.81 | KDM1A (0.46) | PTGS2MAOBCYP11B2CYP11B1HTR2A | |
| Hydrochloric Acid SCHEMBL30216607 | 0.78 | CYP11B2 (0.41) | PTGS2MAOAMAOBACHECYP11B2 | |
| SCHEMBL8854203 | 0.78 | MAOA (0.39) | PTGS2MAOAMAOBACHECYP11B2 | |
| SCHEMBL737836 | 0.78 | MAOA (0.40) | PTGS2MAOAMAOBACHECYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102964371-B | A kind of preparation method of silicon bridge vicinal resistance type cyclopentadiene compounds | SHANGHAI RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) | 2015-08-12 | — | — | CN | claimed |
| CN-102964371-A | Preparation method of silicon-bridged sterically-hindered cyclopentadiene compound | SHANGHAI RES INST CHEMICAL IND | 2013-03-13 | — | — | CN | claimed |
| CN-114599661-B | Transition metal compound, method for preparing the same, and catalyst composition comprising the same | 株式会社LG化学 | 2024-03-12 | — | — | CN | disclosed |
| CN-114599661-A | Transition metal compound, method for preparing the same, and catalyst composition comprising the same | 株式会社LG化学 | 2022-06-07 | — | — | CN | disclosed |
| CN-112105654-A | Curable resin mixture, curable resin composition, and cured product thereof | 日本化药株式会社 | 2020-12-18 | — | — | CN | disclosed |
| WO-2020031935-A1 | CURABLE RESIN MIXTURE, CURABLE RESIN COMPOSITION, AND CURED PRODUCT | 日本化薬株式会社 | 2020-02-13 | — | — | WO | disclosed |
| CN-102939311-B | The method for preparing the load type catalyst system for olefinic polymerization, the catalyst system and application thereof | 巴塞尔聚烯烃股份有限公司 | 2017-10-24 | — | — | CN | disclosed |
| CN-102964371-B | A kind of preparation method of silicon bridge vicinal resistance type cyclopentadiene compounds | SHANGHAI RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) | 2015-08-12 | — | — | CN | disclosed |
| CN-102964371-A | Preparation method of silicon-bridged sterically-hindered cyclopentadiene compound | SHANGHAI RES INST CHEMICAL IND | 2013-03-13 | — | — | CN | disclosed |
| EP-2311811-A1 | NOVEL SPIRO COMPOUND, AND PHARMACEUTICAL PREPARATION COMPRISING THE SAME | Kowa Company, Ltd. (JP) | 2011-04-20 | — | — | EP | disclosed |
| US-20100022572-A1 | NOVEL SPIRO COMPOUND AND MEDICINE COMPRISING THE SAME | KOWA COMPANY, LTD. (JP) | 2010-01-28 | — | — | US | disclosed |
| EP-0985674-B1 | ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS | MITSUBISHI CHEM CORP (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0834519-B1 | CATALYST FOR POLYOLEFIN PRODUCTION AND PROCESS FOR PRODUCING POLYOLEFIN | JAPAN POLYOLEFINS CO LTD (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-6255515-B1 | COORDINATION POLYMERIZATION CATALYSTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-03 | — | — | US | disclosed |
| US-6121182-A | A METALLOCENE CATALYST FOR POLYMERIZATION OF ISOTACTIC POLYOLEFINS WITH HIGH RIGIDITY AND HIGH MELTING POINT, USEFUL AS INDUSTRIAL MATERIAL FOR AUTOMOBILES | JAPAN POLYOLAFINS CO., LTD. (JP) | 2000-09-19 | — | — | US | disclosed |
| EP-0985674-A1 | ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-03-15 | — | — | EP | disclosed |
| EP-0617044-B1 | Process for preparing cyclopentadienyl group-containing silicon compound or cyclopentadienyl group-containing germanium compound | MITSUI CHEMICALS INC (JP) | 1999-01-20 | — | — | EP | disclosed |
| EP-0834519-A1 | CATALYST FOR POLYOLEFIN PRODUCTION AND PROCESS FOR PRODUCING POLYOLEFIN | Japan Polyolefins Co., Ltd. (JP) | 1998-04-08 | — | — | EP | disclosed |
| US-5360921-A | REACTING LITHIUM, SODIUM OR POTASSIUM SALT OF A CYCLOPENTADIENE DERIVATIVE WITH A SILICON OR GERMANIUM HALIDE COMPOUND IN THE PRESENCE OF A CYANIDE OR A THIOCYANATE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| EP-0617044-A2 | Process for preparing cyclopentadienyl group-containing silicon compound or cyclopentadienyl group-containing germanium compound | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022572-A1 | NOVEL SPIRO COMPOUND AND MEDICINE COMPRISING THE SAME | REN, SLC5A1, SLC10A1 | PTGS2 1410/4885MAOA 4728/4885MAOB 4497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.