Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA3 | P15088 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 7/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.36 |
| ▸ | ACE | P12821 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378782 | 0.78 | MME (0.50) | CPA3FOLH1MMEACEALDH1A1 | |
| SCHEMBL28526383 | 0.67 | MME (0.55) | CPA3FOLH1MMP2MMECTRB1 | |
| SCHEMBL892711 | 0.65 | HDAC1 (0.45) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8973724 | 0.65 | ANPEP (0.60) | CPA3FOLH1MMECTRB1 | |
| SCHEMBL8522559 | 0.62 | MME (0.60) | CPA3FOLH1MME | |
| SCHEMBL28443386 | 0.62 | ANPEP (0.52) | CPA3FOLH1MMECTRB1ACE | |
| SCHEMBL1559014 | 0.57 | FOLH1 (1.00) | CPA3FOLH1MME | |
| SCHEMBL1464853 | 0.57 | FOLH1 (1.00) | CPA3FOLH1MME | |
| SCHEMBL8837483 | 0.57 | CTRB1 (0.73) | CPA3FOLH1MMECTRB1ACE | |
| SCHEMBL8837460 | 0.57 | MME (0.73) | CPA3FOLH1MMECTRB1ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993009101-A1 | MERCAPTO-AMIDE DERIVATIVES AS INHIBITORS OF THE NEUTRAL ENDOPEPTIDASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-13 | — | — | WO | disclosed |