Sugi Predict

Sugi Predict / Compounds / SCHEMBL119374

SCHEMBL119374

SCHEMBL119374

Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C(=O)NCC(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ PTGES O14684 1/20 0.35
▸ GABRA5 P31644 5/20 0.35
▸ CA1 P00915 1/20 0.34
▸ CA2 P00918 1/20 0.34
▸ ULK1 O75385 1/20 0.33
▸ ORAI1 Q96D31 7/20 0.33
▸ ELOVL6 Q9H5J4 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ TP53 P04637 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ ALPG P10696 1/20 0.32
▸ ALOX12 P18054 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ TTK P33981 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluralaner SCHEMBL8513367 0.94 CA1 (0.32) PTGESGABRA5CA1CA2ORAI1
Fluralaner SCHEMBL8515337 0.94 CA1 (0.32) PTGESGABRA5CA1CA2ORAI1
Fluralaner SCHEMBL121934 0.94 CA1 (0.32) PTGESGABRA5CA1CA2ORAI1
Fluralaner SCHEMBL29362559 0.94 CA1 (0.32) PTGESGABRA5CA1CA2ORAI1
Fluralaner SCHEMBL29399660 0.94 CA1 (0.32) PTGESGABRA5CA1CA2ORAI1
SCHEMBL736901 0.94 PTGES (0.34) PTGESGABRA5CA1CA2ULK1
SCHEMBL17707540 0.93 PTGES (0.32) PTGESGABRA5CA1CA2ULK1
SCHEMBL20921637 0.92 KDM4E (0.32) PTGESCA1CA2ORAI1ELOVL6
SCHEMBL15059547 0.92 TTK (0.36) CA1CA2ORAI1ELOVL6LMNA
SCHEMBL740369 0.92 CA1 (0.34) CA1CA2ORAI1ELOVL6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3646731-A1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-05-06 — — EP claimed
EP-3300602-B1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-03-25 — — EP claimed
EP-3300602-A1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2018-04-04 — — EP claimed
US-20160219872-A1 Foamable Pesticide Compositions And Methods Of Application BASF CORPORATION 2016-08-04 — — US claimed
US-9339030-B2 Foamable pesticide compositions and methods of application BASF CORPORATION (US) 2016-05-17 — — US claimed
US-20150105258-A1 Methods For Controlling Pests BASF CORPORATION (US) 2015-04-16 — — US claimed
US-8980294-B2 Methods for controlling pests BASF CORPORATION (US) 2015-03-17 — — US claimed
US-8940662-B2 Methods for controlling pests BASF CORPORATION (US) 2015-01-27 — — US claimed
US-20140013654-A1 Foamable Pesticide Compositions BASF CORPORATION 2014-01-16 — — US claimed
US-20140017216-A1 PESTICIDAL MIXTURES BAYER CROPSCIENCE LP (US) 2014-01-16 — — US claimed
EP-2470007-A2 FOAMABLE PESTICIDE COMPOSITIONS AND METHODS OF APPLICATION BASF Corporation (US) 2012-07-04 — — EP claimed
US-20120149570-A1 Foamable Pesticide Compositions And Methods Of Application BASF CORPORATION (US) 2012-06-14 — — US claimed
EP-2424370-A2 FOAMABLE PESTICIDE COMPOSITIONS BASF Corporation (US) 2012-03-07 — — EP claimed
EP-2424347-A1 PESTICIDE COMPOSITIONS AND APPLICATORS BASF Corporation (US) 2012-03-07 — — EP claimed
WO-2011025789-A2 FOAMABLE PESTICIDE COMPOSITIONS AND METHODS OF APPLICATION BASF CORPORATION (US) 2011-03-03 — — WO claimed
US-20100322892-A1 PESTICIDE COMPOSITIONS AND APPLICATORS BASF CORPORATION (US) 2010-12-23 — — US claimed
US-20100323897-A1 FOAMABLE PESTICIDE COMPOSITIONS BASF CORPORATION (US) 2010-12-23 — — US claimed
US-20100322990-A1 METHODS FOR CONTROLLING PESTS BASF CORPORATION (US) 2010-12-23 — — US claimed
WO-2010129345-A2 FOAMABLE PESTICIDE COMPOSITIONS BASF CORPORATION (US) 2010-11-11 — — WO claimed
WO-2010127019-A1 PESTICIDE COMPOSITIONS AND APPLICATORS BASF CORPORATION (US) 2010-11-04 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149570-A1 Foamable Pesticide Compositions And Methods Of Application DDT, PLD1, ACHE PTGES 1237/4885GABRA5 2604/4885CA1 929/4885
US-20100323897-A1 FOAMABLE PESTICIDE COMPOSITIONS DDT, PON1, ACHE PTGES 1994/4885GABRA5 3654/4885CA1 2387/4885
US-20100322990-A1 METHODS FOR CONTROLLING PESTS DDT, ACHE, PON1 PTGES 2010/4885GABRA5 3306/4885CA1 2289/4885
US-20100322892-A1 PESTICIDE COMPOSITIONS AND APPLICATORS DDT, ACHE, CHRM2 PTGES 3958/4885GABRA5 4020/4885CA1 2802/4885
US-20140013654-A1 Foamable Pesticide Compositions DDT, PON1, ACHE PTGES 1994/4885GABRA5 3654/4885CA1 2387/4885
US-20150105258-A1 Methods For Controlling Pests DDT, ACHE, PON1 PTGES 2010/4885GABRA5 3306/4885CA1 2289/4885
US-20160219872-A1 Foamable Pesticide Compositions And Methods Of Application DDT, PLD1, ACHE PTGES 1237/4885GABRA5 2604/4885CA1 929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.